e等公務園+學習平臺
MRSA的診斷、治療與醫院感染管制《解答》
01Staphylococcus Aureus(SA)的菌血症，在下列何種情形，最易有合併症(complicated Staphylococcus aureus bacteremia)發生?
- A1.Community-acquired infection
- B2.A positive result of follow-up blood culture at 48-96 hours正解
- C3.Persistent fever at 72 hours
- D4.skin findings suggestive of acute systemic infection ||
02關于fluoroquinolone與MRSA的關係，下列何者有誤?
- A1.Should not be used to treat invasive MRSA infection
- B2.Fluoroquinolone是MRSA皮膚軟組織感染的首選用藥正解
- C3.Fluoroquinolone的使用，會使病人帶有MRSA的機會增加
- D4.Fluoroquinolone的使用，會易selective出MRSA及其他Fluroquinolone抗藥性菌 ||
03關于MRSA的transmission方式，下列何者有誤?
- A1.inhalation of aerosolized droplets from chronic nasal carriers
- B2.Contact with Contaminated inanimated objects
- C3.contact with another individuals colonized intact skin
- D4.以上皆錯 ||正解
04下列那些patients較適合來執行MRSA的activesurveillance screening?
- A1.History of MRSA colonization
- B2.In intensive care
- C3.Extensive contact with health care system
- D4.以上皆是 ||正解
05關于MRSA在public health的重要性，下列何者正確？
- A1.Increased morbidity and mortality
- B2.prolong hospital stay
- C3.Extra hospital costs
- D4.以上皆是 ||正解
06金黃色葡萄球菌容易造成下列何種感染?
- A1.皮膚、軟組織
- B2.骨及關節
- C3.人工管路
- D4.以上皆是 ||正解
07關于MRSA decolonization，下列何者有誤?
- A1.Whole-body Chlorhexidine washing only can not eradicate MRSA colonization
- B2.MRSA nasal colonization appears to precede infection
- C3.No emergence of resistance to agents used for decolonization正解
- D4.mupirocin is drug of choice for eradication of nasal colonization ||
08台灣醫院醫學中心及區域醫院ICU MRSA百分比大約在
- A1.60-80%正解
- B2.40-60%
- C3.20-40%
- D4.0-20% ||
09社區型的MRSA( CA-MRSA)與院內感染之MRSA ( HA-MRSA)，相異處何者有誤?
- A1.CA-MRSA常發生在免疫受損者正解
- B2.HA-MRSA抗藥性程度比CA-MRSA約為高
- C3.CA-MRSA較發生在皮膚軟組織
- D4.HA-MRSA的發生率常與管路有關 ||
10關于MRSA的敘述，何者有誤?
- A1.其抗生素抗藥性主 要是因帶有mec A gene
- B2.對B-lactam抗生素有high affinity正解
- C3.除了Methicillin，Oxacilin無效外，對cephalosporin也有抗藥性
- D4.使用非B-lactam類抗生素，可能有效 ||
11關于Vancomycin的使用，下列何種有誤?
- A1.Inferior to B-lactam for treatment of MRSA bacteremia and endocarditis
- B2.For the treatment of infection due to MRSA isolates with vancomycin MIC>0.5, optimized pk/pd targets may not be achievable正解
- C3.antibiotic of choose of MRSA infection
- D4.There are MRSA MIC creep in some regions of the world ||
12關于 MRSA的敘述，何者有誤?
- A1.Antibiotic use ( particularly cephalosporin & fluroquinolone use) correlates with the risk for MRSA colonization and infection
- B2.The incidence of invasive MRSA infection was 10 times higher among dialysis patients than in general population正解
- C3.The risk of MRSA infection among MRSA colonization patients in ICUs around 10-25%
- D4.MRSA- Colonized residents are frequently transferred between hospitals and long-term care facilities ||
13關于MRSA的active surveillance cultures，可選擇下列哪個部位?
- A1.Anterior nares
- B2.Rectum
- C3.Areas of skin breakdown
- D4.以上皆是 ||正解
14治療CA-MRSA(社區型MRSA)的建議用藥何者不是?
- A1.Clindamycin
- B2.trimethoprim-sulfamethoxazole
- C3.Tetracycline
- D4.Levofloxacin正解
15About Pathogenesis of SA infection，何者有誤?
- A1.Main ecological niche is anterior nares
- B2.Most S. aureus disease caused by the patient `s own bacteria
- C3.colonization increased risk of subsequent infection
- D4.以上皆錯 ||正解